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Completed Prospective Studies Single Incision versus Standard Laparoscopic Appendectomy for Non-Perforated Appendicitis

St. Peter, Shawn D., MD; Adibe, Obinna O., MD; Juang, David, MD; Sharp, Susan W., PhD; Garey, Carissa L., MD; Laituri, Carrie A., MD; Murphy, J. Patrick, MD; Andrews, Walter S., MD; Sharp, Ronald J., MD; Snyder, Charles L., MD; Holcomb III, George W., MD, MBA; Ostlie Daniel J., MD. "Single Incision Versus Standard 3-Port Laparoscopic Appendectomy: A Prospective Randomized Trial." Annals of Surgery. 254, (2011): 586-590.

This is a definitive study in 360 patients with a 90% power. The primary outcome variable is post-operative infection.

Likely there are several secondary variables that will show small differences between groups. This study will precisely quantify these variables to allow for adequate consultation from surgeons to families with children with acute appendicitis. The single-incision approach is not controlled for and surgeons may vary in the technique and equipment they choose to employ.

Because the differences between the two groups are likely to be small and cosmesis is a proposed advantage of single-incision surgery, we are also using a validated tool to measure scar satisfaction at six weeks and six months after the operation.

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