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Pediatric Oncology About the Cancer Center

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Pediatric Oncology About the Cancer Center

About the Cancer Center

Each year, the Division of Pediatric Hematology, Oncology and Bone Marrow Transplantation at Children’s Mercy Kansas City provides comprehensive care to nearly 2,000 children with childhood cancers, sickle cell disease, hemophilia and other blood disorders, with survival rates frequently above national averages. 

Our commitment to clinical research and innovation has helped us earn recognition as one of the top cancer programs for kids in the nation by U.S. News and World Report. Children’s Mercy also has received accreditation from the American College of Surgeons Commission on Cancer and the Foundation for Accreditation of Cellular Therapy.

Cancer Center Staff

Our unique case management system pairs each of our more than 20 board-certified physicians with an advanced practice nurse or physician assistant and a social worker to provide comprehensive pediatric care to our patients and families. Throughout their treatment, our hematology/oncology/BMT patients have the same team. And our team of pediatric hematology/oncology hospitalists are available 24/7 for inpatient hematology, oncology and bone marrow transplant patients.

Clinical Programs

Defining the Future of Childhood Cancer

At any given time, the Division is participating in 80–100 clinical and laboratory trials, including several national trials led by its own investigators. As the primary pediatric cancer provider and the only NCI Children’s Oncology Group institution in the Midwest Cancer Alliance, Children’s Mercy is the pediatric consortium partner for the National Cancer Institute-designated University of Kansas Cancer Center and the Stowers Institute for Medical Research. This partnership offers progress in cutting-edge cancer research to help the plight of children with cancer.

Research Areas

Our team is currently conducting research on a broad range of topics, including neuroblastoma, stem cell function in treating sickle cell disease and Crohn's disease, new treatment for fanconi anemia and T-cell acute lymphoblastic leukemia. Other current research projects include:

Genomic Research

The Center for Pediatric Genomic Medicine and the Experimental Therapeutics in Cancer program are conducting breakthrough research to better understand the genetic causes of pediatric cancer.

Bridging the Gap

The goals of this project are to assess health care provider’s knowledge of the unique needs of childhood cancer survivors, develop a face-to-face meeting and web-based educational series to improve that knowledge, and evaluate performance improvement strategies among selected clinical sites.

Parent Satisfaction in Outpatient Bone Marrow Transplantation Clinic

This two-part study will help us better understand parents' needs and concerns during the outpatient bone marrow transplantation experience.

Effects of Intrathecal Methotrexate

We're currently studying the effects of intrathecal methotrexate on folate metabolism in the cerebrospinal fluid of children with acute lymphoblastic leukemia. 

Elongation Factor Protein

This study will broaden our understanding of how proteins and genes interact inside leukemia cells. We think that this will help us better understand how leukemia develops.

Pediatric Formulation of Chemotherapy

This study will help us create a child-friendly version of chemotherapy drugs that are as effective as the originally available commercial version.

Immunotherapy for GD2 Positive Tumors

Our researchers are looking to discover how joining the anti-GD2 antibody to T-cells can provide protection from viruses and kill cancer cells.

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