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Neurology Research

Members of the Division of Neurology at Children's Mercy Hospital is involved in several research areas and have both active and pending studies covering a wide range of neurological and neuro-genetic syndromes.

Research Areas

  • Epilepsy
    • Evaluation of the ketogenic diet and quality of life in children's with intractable epilepsy.
    • Increasing the use of Seaizure Action Plans in the Child Neurology Clinic.
    • Levetiracetam Serum Concentration in children between 0 and 18 years of age treated for epilepsy: Correlation with clinical response and tolerability.
    • Lacosamide : A Multicenter, Open-Label Study To Investigate The Safety, Tolerability, And Pharmacokinetics Of Lacosamide (LCM) Oral Solution (Syrup) As Adjunctive Therapy In Children With Partial-Onset Seizures.
    • Lacosamide: An Open-Label Study To Determine Safety,Tolerability, And Efficacy Of Long-Term Oral Lacosamide (LCM) As Adjunctive Therapy In Children With Epilepsy.
    • Ketogenic Diet Success Predictors in Patients with Intractable Epilepsy. 
    • Intraoperative ECoG monitoring and seizure outcomes. 
    • Delivery of Antepileptic Medications to Patient's Bedside in the Setting of Prolonged Epileptic Seizure with or without Status Epilepticus: Retrospective Chart Review Protocol/Quaility Improvement.
  • Headache
    • Treatment of headache with non-drug therapies to alleviate migraine headaches.
    • CHAMP, The Childhood and Adolescent Migraine Prevention Study. 
  • Kernicterus
    • Evaluation and treatment of children with possible brain damage or neurodevelopmental disorders due to excessive newborn jaundice, including kernicterus and BIN (bilirubin-induced brain disorders). 
    • Investigations of the role of bilirubin in neurological damage.
    • Kernicterus, Jaundice, and Bilrubin Induced Neurological Disorders.
    • Bind: Neonatal Bilirubin Induced Neurologic Dysfunction in Developing Countries.
  • Movement Disorders
    • Medtronic Deep Brain Stimulation (DBS) Therapy for Dystonia. 
  • Neurogentics
    • Diagnostic Utilization of Microarray Comparative Genomic Hybridization (aCGH) in Neurodevelopmental Disorders. 
  • Neuromuscular
    • Spinal Muscular Atrophy (SMA) Biomarkers in the Immediate Postnatal Period of Development. 

Research Highlights

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