Pharmacology and Toxicology GOLDILOKS
Pharmacology and Toxicology GOLDILOKS

GOLDILOKS® Initiative

The GOLDILOKS® initiative aims to change how medication is prescribed for children and deliver on the promise of precision medicine.

GOLDILOKS® will not be a one-size fits all approach. Depending on the disease and the drug being evaluated, information may be gathered from genetics, ontogeny, environment, history and physical, and other factors that influence variability in how a patient responds to specific drugs. Sophisticated mathematical models will be developed and integrated into proprietary decision support software to assist providers in determining the best drug treatment and the dose that is just right for each individual patient.

Research in Progress

The GOLDILOKS concept is applicable to medications across all subspecialties. The following specialties are currently active in exploring the development and application of GOLDILOKS at Children’s Mercy:

  • Asthma/Allergy
  • Cardiology
  • Developmental and Behavioral Medicine
  • Gastroenterology
  • Hematology/Oncology/BMT
  • Neonatology
  • Infectious Diseases
  • Rehabilitation Medicine
  • Rheumatology

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