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Opioid Overdose Reversal Medication

Opioid overdose reversal medication (Narcan®)

Naloxone (Narcan®) is an emergency overdose reversal medication. When used properly, it can instantly revive someone who is experiencing an overdose until medical help arrives.

Opioids are prescription drugs, such as Percocet and OxyContin. They are also illegal drugs such as heroin. Opioids are very dangerous when misused.

Anyone in Missouri can legally buy Naloxone at pharmacies such as Walgreen’s, CVS, and Children’s Mercy without a prescription. It is also available free from the National Council on Alcoholism and Drug Abuse.

If you have Naloxone in your home, store it in a locked cabinet, drawer, box or other space that is out of the reach of children or pets.

How to avoid opioid overdose


  • Take medicine only if it has been prescribed to you by your doctor

  • Do not take more medicine than instructed

  • Call a doctor if your pain gets worse

  • Never mix pain medicines with alcohol, sleeping pills, or any illegal substances

  • Learn the signs of drug overdose

  • Learn how to use Naloxone safely

  • Teach your family and friends how to respond to an overdose

  • Dispose of unused medication properly

To learn more:

SAMHSA Opioid Overdose Prevention Toolkit