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Preventive Cardiology Research

To help advance the practice of pediatric preventative cardiology, our team actively participates in research. Currently, we are involved in three research studies, as described below.

Second-hand smoke exposure and the vascular system of children

We’re studying the effects of second-hand smoke exposure on the vascular system of children with dyslipidemia. Participants in this study have abnormal cholesterol, some have exposure to second-hand smoke, and some have no exposure to second-hand smoke. This study examines the blood vessels of those exposed second-hand smoke and how this exposure affects their blood vessels, compared to the blood vessels of children who are not exposed second-hand smoke. Participation is completely voluntary, and able to be completed during your clinic visit. Participants are asked to provide a urine specimen for the study. Participation is kept confidential. 

Genetics and high cholesterol in children

The next research study our team is involved in is a genetic analysis of children with high cholesterol. This study uses genetics, via a cheek swab, to help tailor a statin medications (a type of medication used to treat high cholesterol), based on the genetic profile of the person. The goal of this study is to help better prescribe statins to patients for the most effective treatment. Participation in this study is also completely voluntary, able to completed during your clinic visit, and your participation is kept confidential.

Effects of Lipoprotein A in children

We’re studying the effects of lipoprotein a on the vasculature in children. In order to participate in the study one must be between ages 9-18, have a measured LPa (either high or low). Pulse wave velocity consists of measuring the pulse wave transit time between the carotid and femoral arteries, using a blood pressure cuff and a small sensor on the neck over the carotid artery. Pulse wave velocity measures the stiffness in the arteries and total vascular stiffness. Participation is voluntary and able to be completed during your visit. Your participation is kept confidential.

The Children's Mercy Research Institute

The Children’s Mercy Research Institute at Children's Mercy is creating an integrated research environment where no boundaries exist between science and medicine. In our quest to find answers to pediatric medicine’s most challenging questions, we are collaborating with physicians, scientists, academic colleagues, philanthropic partners and others within our community, and around the world.