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Children's Mercy operates the largest pediatric kidney transplant program in Missouri and Kansas. The transplant program complements the nationally recognized pediatric dialysis program and is a key component of the Division of Nephrology, which ranks as one of the top programs in the country by U. S. News and World Report.

Our multidisciplinary team works with referring physicians before, during and after a transplant to ensure effective continuity of care for pediatric transplant recipients and their families. We have established an outstanding national reputation for patient care and outcomes. 

Kidney failure


Having kidney failure means that your kidneys are not working well enough to keep you healthy. End-stage kidney disease (ESKD) is also sometimes called kidney failure.

Causes of kidney failure in children:

  • Infections
  • Congenital conditions (abnormalities of the kidneys you are born with)
  • Genetic conditions (abnormalities of the kidneys that you inherit)
  • Autoimmune diseases
  • High blood pressure
  • Medication
  • Traumatic injury to the kidney
  • Inflammation
  • Kidney blockage
  • Unknown reasons

Treatment of kidney failure


There is no for cure for kidney failure, but there is treatment:

  • Dialysis
    • Hemodialysis (HD)
    • Peritoneal dialysis (PD)
  • Diet
  • Medications
  • Kidney Transplant
    • Living donation
    • Deceased donation

A kidney transplant is a treatment for kidney failure. It is not a cure.

  • A kidney transplant requires a surgery in which a person with kidney failure gets one new, healthy kidney from a donor.
  • There are two types of kidney transplant donors:
    • Living donor = Person voluntarily donates kidney to recipient.
    • Deceased donor = Donor has died, and family approves donation of loved one’s kidneys.
  • You/your child can live a healthy life with just one kidney.
  • On average, a kidney transplant will last about 15 years.
  • You/your child will need to take transplant medications for as long as the kidney is working.
  • You/your child will likely need more than one transplant in his/her lifetime.

The Kidney Transplant Team


For a transplant to be successful, many people work together. The most important members of the Kidney Transplant Team are you/you as a parent and your children. The members of the transplant team are listed below. Many others work with the team as well, such as urologists, transplant unit nurses (5 Sutherland Tower and Intensive Care), clinic nurses in the Kidney Center and dialysis nurses. Your transplant team wants you to be involved as much as possible in your/your child’s care. It is important for you to ask the team any questions you may have and to report any changes in how you/your child is feeling before and after the transplant.

  • Nephrologists (kidney doctors)
  • Transplant surgeons
  • Nurse practitioners
  • Dialysis nurses
  • Dialysis technicians
  • Transport coordinators
  • Psychologists
  • Social workers
  • Dieticians
  • Financial coordinators
  • Child life specialists
  • Pharmacists
  • Chaplains
  • Hospital-based school teachers

Before getting a kidney transplant, you/your child must have a complete evaluation, to make sure you/your child are healthy enough to be transplanted. Learn more about the transplant evaluation and what to expect after surgery.

Pediatric Kidney Transplant Education Book

Our Pediatric Kidney Transplant Education Book: A Guide for Patients and Families was created to help you and your family throughout the entire transplant process and includes detailed instructions about your/your child’s transplant. Read the guidebook here or download a copy.

Kidney transplant survival rates above the national average

 

Children’s Mercy is a national leader in pediatric kidney transplant outcomes. According to data from the Scientific Registry of Transplant Recipients (SRTR), pediatric patient and graft (transplanted organ) outcomes at Children's Mercy are among the nation’s best.  

Although we see the most serious cases, the latest SRTR data shows that our 3 year hazard ratio—a figure that characterizes the risk of a transplant failing within 3 years of receiving a transplant—is the best nationally. With a hazard ratio value of 0.41 and 100% 3-year graft survival, this equates to an estimated 59% lower risk of a transplant failing at Children’s Mercy compared to a program with outcomes that meet the average of all pediatric kidney transplant programs in the country.

Our transplant team is happy to discuss this data and our expertise with you as you are selecting a care team for your child.

Children's Mercy Transplant Center

At Children’s Mercy, one of our greatest achievements is helping critically-ill children avoid transplant. Still, some children require a transplant to survive, and when that’s the case, our expert clinicians are able to meet that need.

Nationally ranked by U.S. News & World Report

Nationally ranked by U.S. News & World Report

When your child comes to Children's Mercy for care, they're getting a nationally recognized team of experts and an entire system of support.

  • Multidisciplinary transplant team including pediatric specialists in nephrology, transplant surgery, urology and anesthesiology.

  • Availability of transplant coordinator, physician and surgeon 24 hours per day, seven days a week

  • Pharmacokinetic modeling of immunosuppressive medications.

  • Laparoscopic kidney donation.

  • Opportunity to participate in research protocols of new therapies for transplant recipients.

  • Transition program for transplant recipients.

  • Medically-supervised summer camp experience for dialysis and transplant patients.

  • Ronald McDonald House or the Ronald McDonald Family Room accommodations for patient families.

Stories

En bloc Liver/Kidney Transplant: Trevion’s Story

When you see 13-year-old Trevion goofing around with his dad and sisters and playing basketball with his friends, you would never know that he recently had a double organ transplant to replace his liver and kidney. Trevion was the first Children’s Mercy Kansas City patient to receive an en bloc liver/kidney transplant.

Meet Trevion
A Black, teenage boy with dreadlocks smiles at the camera.

Mother-Daughter Kidney Transplant: Clara's story

Born with one kidney, Clara faced many health challenges. With help from Children's Mercy and mom, Vivi, Clara continues exploring the world and singing along to her mom's favorite tunes. 

Meet Clara

Inside Pediatrics: Jack's story

Two-year-old Jack needs daily dialysis, care from the region’s top pediatric nephrologists and a kidney transplant to survive. While some kids wait months for a kidney, Jack already has a donor: his dad.

A better quality of life: Hayden's story

Hayden Murnahan defied the odds when he received a long-distance kidney donation via private plane for a second transplant.

Meet Hayden
Hayden Murnahan being examined at a Children's Mercy clinic by Dr. Chadha.

Kidney transplant: Isaac's and Colin's stories

Isaac Schroeder, a 2 ½-year-old patient from Omaha, Neb., and his mother celebrate the one-year anniversary of Isaac’s lifesaving kidney transplant at Children’s Mercy. Meanwhile 18-year-old Colin Martin recovers from a kidney transplant made possible by his brother, William. This was the first brother-to-brother transplant performed at Children’s Mercy, and both young men are doing well.

Kidney transplant: Josiah’s story

Josiah's and his family faced unforeseen challenges on his journey to receiving a kidney transplant. Fortunately, the transplant not only saved Josiah's life, it brought him and his family closer together.

Meet Josiah
Kidney transplant patient, Josiah, at Children's Mercy.

Advancing kidney transplant care through research


Members of the Children's Mercy Kidney Transplant Team take part in local, regional and national research that aims to find innovative treatments for children who have kidney failure.

  • Evaluation of immunosuppressive dosing regimens as part of our quality improvement activities has resulted in modification of medication administration schedules and more prompt achievement of therapeutic drug levels. 

  • We are working with colleagues in the Center for Personalized Medicine and Therapeutic Innovation to explore the influence of genomic-based variations in patient drug metabolism characteristics on individualized treatment regimens.

  • Our program is a regular participant in national industry-sponsored pharmaceutical studies. Current protocols are addressing the use of erythropoietic stimulating agents, vitamin D and anti-viral agents in transplant recipients.

  • We are one of a select group of pediatric transplant programs in the country participating in a study sponsored by the National Institutes of Health of antihypertensive therapy in pediatric transplant patients.

  • The transplant, dialysis and general nephrology programs are active members of the North American Pediatric Renal Trials and Collaborative Studies (NAPRTCS). Activities include data entry into the transplant, dialysis and chronic kidney disease registries, participation in the benchmarking project, and frequent patient entry into prospective clinical trials.

Visit the Donate Life organization to learn more about organ donation, registration, news, and events.