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Clinical Pathways promote evidence based, safe, and high-value care for patients by providing clinical recommendations and standard processes. They are developed by multidisciplinary committees of subject matter experts, informed by methodical review of available evidence and consensus among committee members.  

The Severe hypertriglyceridemia (SHTG) synopsis provides a high level overview of the care standards employed for this Clinical Pathway. 

Algorithms associated with this Clinical Pathway: 

Inclusion and exclusion criteria 


  • SHTG related to: 
    • Diabetes and insulin resistance.
    • Hematologic-oncologic processes. 
    • Renal disease.
    • TPN use.

Committee members involved in the development of this Clinical Pathway: 

  • E Maris Wee, MD | Department of Endocrinology – Fellow| Committee chair 
  • M. Feldt, DO | Department of Endocrinology | Committee chair mentor  
  • R. McDonough, DO |Department of Endocrinology | Committee member 
  • L. Fullenkamp, MD, JD | Department of Hospital Medicine | Committee member  
  • N. Ibrahimi, MD | Department of Gastroenterology | Committee member  
  • A. Wagner, DO | Department of Critical Care Medicine | Committee member  
  • L. Enlow, PharmD | Department of Pharmacy | Committee member  
  • D. Porter, MSN, RN | 6 Henson Tower Nursing Director | Committee member 
  • K. Berg, MD, FAAP | Department of Evidence Based Practice and Hospital Medicine  
  • A. Melanson, OTD, OTR/L | Department of Evidence Based Practice  
  • J. A. Bartlett, PhD, RN | Department of Evidence Based Practice  

Publication dates: 

  • Finalized date: October 2021 
  • Next expected revision date: October 2024 

Concerns with content:

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These pathways do not establish a standard of care to be followed in every case. It is recognized that each case is different, and those individuals involved in providing health care are expected to use their judgment in determining what is in the best interests of the patient based on the circumstances existing at the time. It is impossible to anticipate all possible situations that may exist and to prepare a pathway for each. Accordingly, these pathways should guide care with the understanding that departures from them may be required at times.