Accelerating research through Areas of Emphasis
Researchers at CMRI tap into AOE support in a variety of ways, advancing their lines of scientific inquiry and accelerating their discoveries. As an example, Jennifer L. Goldman, MD, MS, and Jenna Miller, MD, FAAP, together are investigating why a commonly used antibiotic, Bactrim, causes life-threatening reactions in a small percentage of patients who receive this drug that is safe for most people.
Drs. Goldman and Miller are engaging multiple disciplines to define a previously unrecognized severe reaction and identify the potential genetic factors that place certain patients at high risk.
For this research project, the investigators leverage the support of AOE expertise within Precision Therapeutics, Genomic Medicine and Health Care Innovation. Also critical to the success of the study are specialists within Infectious Diseases, proteomics and drug metabolism experts in Clinical Pharmacology, experts in the Genome Center, and CMRI’s biorepository and skilled resource coordinators.