Research Studies and Clinical Trials Search
Results
Acute Brain Injury Detection for Patients on ECMO Using Portable MRI
This study is for patients: • Admitted to the NICU, PICU or CICU • Undergoing ECMO as part of clinical care • Can have a portable MRI exam at different times while on ECMO...
This study is for patients: • Admitted to the NICU, PICU or CICU • Undergoing ECMO as part of clinical care • Can have a portable MRI exam at different times while on ECMO The goal of our study is to learn if using a low-field strength MRI, a portable MRI, can improve our understanding of timing and type of acute brain injuries during extracorporeal membrane oxygenation (ECMO). All portable MRI exams are reviewed by a Children's Mercy radiologist. There is no additional cost to participating in the study.
Medications for Children in the Intensive Care Unit: Health information and extra blood and body fluid samples saved for research
This research includes children: • Who are sick and in the intensive care unit and receiving one or more medications to treat that illness. • Health information collected and extra blood and body fluids that are not needed to care for the child will be saved and used to learn...
This research includes children: • Who are sick and in the intensive care unit and receiving one or more medications to treat that illness. • Health information collected and extra blood and body fluids that are not needed to care for the child will be saved and used to learn more about these body differences and the impact of medication levels during an illness. When children are sick, their bodies may react differently to medications during sickness compared to when their bodies are healthy. Children with medically complex conditions who regularly take medications may experience even more differences when they are sick. Some of the differences during sickness can include swelling, fevers, high heart rate, changes in their liver or kidney function, changes in the way their body breaks down or uses medications, or other differences that researchers are still determining. These differences could result in medication that is not given at a high enough amount to treat the illness, or too much of an amount that could cause other problems in the body. Researchers will learn more about these body differences and the impact of medication levels during an illness.
Multi-Organ Dysfunction Syndrome (MODS): Research including children with MODS and looking at their unique immune function
This research includes children: • Who have a severe infection called sepsis, which is causing two or more organs to work poorly (MODS). When sepsis and MODS happen, the child's immune function may be too low and/or the amount of inflammation in the body...
This research includes children: • Who have a severe infection called sepsis, which is causing two or more organs to work poorly (MODS). When sepsis and MODS happen, the child's immune function may be too low and/or the amount of inflammation in the body organs may be too high. At this time, only a research laboratory can do this special testing to determine a child's unique immune function. As part of this research study, a blood sample is sent to the research laboratory to get results of the child's unique immune function and level of inflammation.
Portable MRI (pMRI) for Pediatric Hypoxic Ischemic Brain Injury (HIBI): Targeting early diagnosis and Improve Outcomes
This study is for patients: • Admitted to the NICU, PICU or CICU • Have a standard MRI or CT already ordered. • Can have a portable MRI exam at the bedside...
This study is for patients: • Admitted to the NICU, PICU or CICU • Have a standard MRI or CT already ordered. • Can have a portable MRI exam at the bedside The goal of our study is to determine the sensitivity and specificity of a portable MRI compared to a standard MRI. There are many patients in the ICU setting that cannot travel to radiology to obtain an MRI. By using a portable MRI machine, the team can detect and treat acute ischemic brain injuries earlier and have better patient outcomes.