About the Study

Multi-organ Dysfunction Syndrome: A study to reverse the inflammation causing multi-organ problems in very sick children

This study is being done for kids: • Who has a severe infection called sepsis • Be able to provide several blood samples This study is for very sick kids that have a severe infection called sepsis. That infection is causing two or more body organs to work poorly. When this happens, the immune function may be too low and/or the amount of inflammation in the body organs may be too high. At this time, doctors don't know which issue the immune system has. This study looks at the immune function and can figure out if, in certain situations, the anti-inflammatory medicine called Anakinra, could be helpful to decrease organ inflammation with the goal to recover and recover more quickly.

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Full Study Name: Inflammation Reversal in Very Sick Children (PRECISE)