Informatics and Data Resources
i2b2 (DORA) — DORA is a de-identified data repository of Children’s Mercy electronic medical records based on Cerner's implementation of standard i2b2 framework. It allows Children’s Mercy Research Institute researchers to conduct feasibility analysis, analyze retrospective data without PHI, inform quality initiatives and generate hypotheses.
Pediatric Health Information System® (PHIS) — Children’s Mercy is a member of the Children’s Hospital Association and has access to PHIS, a comparative pediatric database. This database includes clinical and resource utilization data for inpatient, ambulatory surgery, emergency department and observation unit patient encounters for more than 45 children's hospitals.
Cerner Health Facts® — Cerner Health Facts® is a data warehouse of HIPAA-compliant de-identified electronic health record level detailed data from participating hospitals and clinics. Pharmacy orders, laboratory results, discrete clinical findings, demographic and billing information are available for a wide variety of research projects and analysis.
REDCap — REDCap is a secure HIPAA-compliant web application for building and managing online surveys and databases.
Supercomputing Cluster — The Children’s Mercy supercomputer is located within a secure dedicated data center. The computing cluster consists of nearly 2,600 cores and over 15TB of total RAM. Also available are an Edico Dragen Genomics Bio-IT processor and a 10-node test cluster. Children’s Mercy has more than 3PB of high-performance storage.
Bioinformatics Applications — Deployed on Children’s Mercy clusters are the latest versions of Apache HADOOP, Partek Flow & Genetics Suite, GATK, Bowtie, TopHat, Cufflinks, R, Python, BreakDancer, et al., and many locally developed software suites to aid in next-gen sequencing analysis.
Statistics Applications — Statistical analysis applications such as SAS, SPSS and R are available for use by researchers.
Cerner’s PowerTrials® — Cerner’s PowerTrials® integrates research processes into the workflow of Cerner’s electronic health record, ensuring that clinical research and clinical care share relevant data. It is used to screen potential participants by coding inclusion/exclusion criteria into a set of rules, then tracks enrollment status.