Younger Lab
About the Lab
The vast majority of rare diseases in children are thought to result from underlying variations in the sequence of their DNA. However, distinguishing the specific genetic variants that cause disease and deciphering their functional consequences remains a major challenge. The Younger Lab integrates a series of research programs to accelerate the process of translating the clinical detection of genetic variants into meaningful and actionable biological discoveries.
Leader
Dr. Scott Younger is the Director of Disease Gene Engineering within the Genomic Medicine Center at Children's Mercy Kansas City. He has extensive experience working with high-throughput sequencing-based screening technologies and is leading efforts to dissect the molecular mechanisms through which rare genetic variants identified in patients at Children's Mercy lead to disease.
Dr. Younger came to Children's Mercy from the Broad Institute of MIT and Harvard where his group worked on the development of new methodologies to expand the utility of CRISPR-based genetic screens. Prior to working at the Broad Institute, he completed his postdoctoral studies at Harvard University as an American Cancer Society Fellow. He holds a Ph.D. in cell and molecular biology from UT Southwestern Medical Center. He also received an M.S. in biotechnology from the University of Texas at San Antonio and a B.S.I. in bioinformatics from Baylor University.
- Research Areas
- Labs and Research Teams
- ACCESS Behavioral Health Lab
- Baby Health and Behavior Lab
- Baby Lab
- Bactrim Lung Failure Team
- Behavioral Pain Innovations Lab
- Center for Children’s Healthy Lifestyles & Nutrition
- Community Engaged Research Team
- Developmental and Behavioral Health Research Group
- Fridley Lab
- Laboratory of Immunogenomics
- Milkovich Lab
- Nadler Lab
- Pediatric Brain Cancer Research Team/Yadav Lab
- Ramsey Lab
- Sullivant Lab
- Varberg Lab
- Younger Lab
Director, Disease Gene Engineering; Assistant Professor of Pediatrics, University of Missouri-Kansas City School of Medicine; Research Assistant Professor of Pediatrics, University of Kansas School of Medicine