Blood and Marrow Transplant
Children's Mercy provides expert bone marrow transplant services for patients with a variety of needs.

Blood and Marrow Transplant

If your child requires a blood and marrow transplant (BMT) or cellular therapy, you want the best care possible from a team of experienced medical professionals who care about your child as much as you do.

At Children’s Mercy, we have the resources, knowledge and expertise to not only help your child survive a life-threatening illness, but to thrive after treatment and live a healthy life. 

Since the program began, more than 400 children have received life-saving blood and marrow transplants. 

Our program is accredited by the Foundation for the Accreditation of Cellular Therapy (FACT) and the National Marrow Donor Program. We are also a member of several organizations that help ensure your child receives the best care possible, including:

  • Center for International Blood and Marrow Transplant Research (CIBMTR)
  • Pediatric Blood and Marrow Transplant Consortium (PBMTC)
  • American Society for Blood and Marrow Transplantation
  • Children’s Oncology Group (COG)

Transplant options for every child

One of the first questions families ask us is will my child have a donor?

When we meet a child in need of a transplant, we search all available donor options. Doing so means we can quickly find the best solution each child. As a transplant center for the National Marrow Donor Program (NMDP), Children’s Mercy has access to donor registries throughout the world.

There are two types of transplant:

  • Allogeneic transplant is when cells are obtained from someone else. 
  • Autologous transplant is when the patient’s own cells are used.

Types of donors include:

  • Matched Siblings
  • Partially matched related donors (including parents), also called a haploidentical transplant
  • Unrelated donors from a volunteer registry
  • Umbilical Cord Blood Units

We can obtain the healthy cells from the donor in different ways. These include:

  • Bone marrow – typically taken from the back of the hip bones from the donor
  • Peripheral blood - taken from the blood of the donor by using a machine to filter out the stem cells
  • Cord blood transplants – using stem cells from donated umbilical cords 

Meet Connor

Advanced treatment for diverse disorders

Each year, the BMT Program performs approximately 40 transplants for children up to age 21. Transplants are done to treat varying forms and stages of cancers. We also use transplantation to treat immune system (immunologic) disorders, blood (hematologic) disorders, and metabolic disorders.  

The wide range of diagnoses we treat with transplant include:

  • Acute Lymphoblastic Leukemia (ALL)
  • Acute Myelogenous Leukemia (AML)
  • Chronic Myelocytic Leukemia (CML)
  • Fanconi Anemia
  • Hodgkin’s Lymphoma
  • Hurler Syndrome
  • Juvenile Myelomonocytic Leukemia (JMML)
  • Non-Hodgkin’s Lymphoma
  • Severe Aplastic Anemia
  • Solid Childhood Tumors
  • Wilm’s tumor
  • Neuroblastoma
  • Sickle Cell Disease 
  • Thalassemia

Children’s Mercy also has experience with rare disorders, successfully treating:

  • Adrenoleukodystrophy (ALD)
  • Beta Thalassemia
  • Blackfan Diamond Syndrome
  • CD3 Delta Def
  • CD40 Ligand
  • Chediak-Higashi Syndrome
  • Congenital Dyserythropoetic Anemia
  • Crohn’s- IL-10 Receptor Mutation
  • Dyskeratosis Congenita
  • Glanzmann Thrombasthenia
  • Hemophagocytic lymphohistiocytosis (HLH)
  • Hurler Syndrome
  • I-Cell Disease
  • Omenn Syndrome
  • Osteopetrosis
  • Pansclerotic Morphea
  • Porphyria
  • Wiskott-Aldrich Syndrome

Your care team

The process of caring for a child who needs a transplant is complex and requires the skills and expertise of a team of specialists. All team members specialize in blood and marrow treatment. The team is led by Section Chief, Rakesh Goyal, MD.

Learn about your care team.

Your experience at Children’s Mercy

Learn more about what to expect before, during and after transplant at Children’s Mercy.

Research and innovation

Learn more about the latest treatment options and research frontiers at Children's Mercy, like CAR T-cell immunotherapy and mini-transplants for children with SCID (severe immune system defect).

Annual BMT reunion

Please join us at Union Station for breakfast, admission to Science City and fun activities!

Saturday April 21, 2018
9:30 a.m.
Union Station
30 W Pershing Road
Kansas City, MO

Please feel free to explore Science City at your own pace with your family following breakfast and activities.

RSVP to Lindsey MacDonald or Sarah Pearson by phone at (816) 302-6808 or by emailing sbpearson@cmh.edu

Contact us

The Division of Pediatric Hematology, Oncology and Blood and Marrow Transplantation is recognized by U.S. News and World Report as one of the best programs in the country.

Interested in learning more about the BMT and cellular therapies program? Please contact Dr. Goyal and the care team. 

Patients and Families: Call (816) 302-6808 

Referring Health Care Providers: Call (816) 302-6808 or email HOBMTNewPatientReferral@cmh.edu

The Division of Pediatric Hematology, Oncology and Bone Marrow Transplantation

Each year, the Division of Pediatric Hematology, Oncology and Bone Marrow Transplantation at Children’s Mercy Kansas City provides comprehensive care to nearly 2,000 children with childhood cancers, sickle cell disease, hemophilia and other blood disorders, with survival rates frequently above national averages. At any given time, the Division is participating in 80–100 clinical and laboratory trials, including several national trials led by its own investigators. As the primary pediatric cancer provider and the only NCI Children’s Oncology Group institution in the Midwest Cancer Alliance, Children’s Mercy is the pediatric consortium partner for the National Cancer Institute-designated The University of Kansas Cancer Center and the Stowers Institute for Medical Research. This partnership offers progress in cutting-edge cancer research to help the plight of children with cancer. The Division also has received accreditation from the American College of Surgeons Commission on Cancer and the Foundation for Accreditation of Cellular Therapy.

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