Stats
Another top ten study in EBM (February 14, 2005)
Category: Teaching resources
Here's another nomination for the top ten studies
in EBM.
One of the pitfalls of research evaluating diagnostic tests is spectrum
bias, and this was noted as early as 1978 in
- Problems of spectrum and bias in evaluating the efficacy of
diagnostic tests. Ransohoff DF, Feinstein AR. N Engl J Med 1978:
299(17); 926-30.
[Medline]
[Abstract]
This is a good article to cite, because one of the authors, AR Feinstein,
was pivotal in the development of Clinical Epidemiology, which he defined as
the clinicostatistical study of diseased populations. The intellectual
activities of this territory include the following: the occurrence rates
and geographic distribution of disease; the patterns of natural and
post-therapeutic events that constitute varying clinical courses in the
diverse spectrum of disease; and the clinical appraisal of therapy. --
as quoted in
www.nsite.ca/sackett/uploads/collections/72090908.pdf
I have a brief weblog entry about spectrum bias:
07/08/2008.
