Pediatric Genomic Medicine Facilities
Pediatric Genomic Medicine Facilities
The Center's capital equipment and software tools provide support for our achieving and maintaining CLIA certification and CAP accreditation. Our collection of sequencers and robots allows us to process over 2 Tb of data per week.

Equipment Features

  • Four Illumina HiSeq sequencers – Three Illumina HiSeq 2500 sequencers, two with High output v4 chemistry and One Illumina HiSeq 2000 sequencer
  • Two Illumina MiSeq sequencers
  • Two Illumina cBots
  • Three Perkin Elmer liquid handling robots –JanusR, NGS Express TM and Sciclone
  • Perkin Elmer Chemagen, automated system to extract nucleic acid 
  • Bio-Rad CFX96 Touch TM real-time PCR detection system
  • Life Technologies ViiA 7TM real-time PCR detection system
  • Covaris LE220 96-well plate DNA sonication system
  • Agilent Bioanalyzer 2100 and Tapestation 2200 systems

Genetics Laboratory

The Clinical Molecular Genetics Laboratory is a full service diagnostic laboratory operated by the Department of Pathology and Laboratory Medicine which supports the Genome Center. This laboratory performs Sanger sequencing to confirm genetic variants on DNA sequenced by the Genome Center.

Data Center

The Center's computer resources are located within a dedicated data center with environmental controls, 8 tons of air conditioning, conditioned power, hospital emergency back-up power and substantial UPS capability.

Other Data Center Features

  • 1300-core Linux compute cluster with 6TB of DDR3 RAM
  • head node (12-core Intel Xeon X5670 with 48GB RAM and 500GB SATA drive)
  • pipeline server (12-core Intel Xeon X5670 with 96GB RAM and 1TB SATA hard drive)
  • web servers (12-core Intel Xeon X5670 with 48GB RAM and 500GB SATA drive)
  • database server (12-core Intel Xeon X5670 with 96GB RAM and 16TB SATA drives)
  • database server (16-core Intel Xeon E5-2640 v3 with 256GB RAM and 6TB SSD RAID 5)
  • mongodb server (16-core Intel Xeon E5-2640 v3 with 256GB RAM and 6TB SSD RAID 5)
  • Data Direct Networks Grid Scalar 7K with 360TB usable capacity
  • Isilon X400 storage system with 810TB usable capacity
  • SGI Infinite Storage Gateway disaster recovery and backup appliance with 160TB usable capacity
  • Spectra Logic T950 tape library with 2.5PB usable capacity
  • Spectra Logic nTier Verde with 24TB capacity

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