Pediatric Critical Care Medicine Research
Pediatric Critical Care Medicine Research

The Section of Critical Care at Children's Mercy Kansas City participates in both PALISI (the Pediatric Acute Lung Injury and Sepsis Investigators, a multi-center research consortium) and NACHRI PICU Focus Group (National Association of Children's Hospitals and Related Institutions).

Each of our trainees is expected to complete a minimum of one scholarly project during the course of their fellowship, resulting in the submission of a manuscript to a peer-reviewed publication. In addition, our fellows are expected to present findings at a national meeting.

A crucial first step in this process is the formation of a mentoring relationship with a faculty member (either inside or outside of our division), followed by development of a research question and specific aims and formation of a Scholarship Oversight Committee (SOC). The SOC will meet regularly with the fellow throughout his or her training to monitor the progress of the project, provide guidance and assure that the fellow is engaging in a meaningful and educational scholarly endeavor that will meet the requirements for board certification.

A few of the many research opportunities available at Children's Mercy Hospital include:

  • Personalized Medicine-Pediatric Genomic Medicine
  • Clinical Pharmacology
  • Cardiovascular Research

Critical Care Current Research Activities

 Fellow Scholarly Projects

Fellow Involved

Project Title

Sandeep Arya

Comparison of Near Infrared Spectroscopy (NIRS) with Capillary Refill Time (CRT) in their ability to predict SVO2<70%.

The Relative Impact of High-Risk Unscheduled Transfers to the Pediatric Intensive Care Unit and Subsequent Mortality

 

Asdis Wagner

Parental Perspectives in the PICU Regarding Limitations of Life-Sustaining Therapy, End-of-Life Care, and Do-Not-Resuscitate Orders

Arjun Chandran

Fluid Goals in Cardiac Surgery Patients in the First Post Operative Day

Faculty Scholarly Projects

Faculty Involved

Project Title

Jeremy Affolter

The Association of Central Line-associated Bloodstream Infections with Central Line Utilization Rate and Maintenance Bundle Compliance among types of Pediatric Intensive Care Units.

Assessment of Patient Safety Indicators for Adults Admitted to the Pediatric Intensive Care Unit.

Pediatric Acute Respiratory Distress Syndrome Incidence and Epidemiology (PARDI)

 

Geoff Allen

Genomic Analysis of the Pediatric Systemic Inflammatory Response
Syndrome

The SAFE Extrapolation to Paediatric Intensive Care (SAFE-EPIC) Study

Sedation Management in Pediatric Patients with Acute Respiratory Failure    

             

Paul Bauer

The Relative Impact of High-Risk Unscheduled Transfers to the Pediatric Intensive Care Unit and Subsequent Mortality

QI: Line Entry and Rounding Checklist Utilization

QI: CLABSI group

 

Tara Benton

QI: Pediatric Severe TBI Guideline Implementation

QI: Severe Pediatric Burn Management Guideline Implementation

QI: Line Entry and Rounding Checklist Utilization

QI: Reduction of Pressure Ulcers Related to NIV by Standardizing Equipment

QI: Reduction of Pressure Ulcers Related to Nasal ETTs

 

Jennifer Flint

Single Ventricle Feeding Protocol- A Feeding Protocol for Infants with Single Ventricle Anatomy may Decrease Morbidity and Mortality associated with Feeding Complications including Necrotizing Enterocolitis

BNP levels and ECMO weaning- Utility of BNP Trends during Weaning of Cardiac EMCO

BNP Levels and Post-Extubation Failure-  B-type Natriuretic Peptide:  A Potential Biomarker for Extubation Failure in Infants after Cardiac Surgery

Laparoscopic Gastrostomy Tube Placement in Patients with Complex Congenital Heart Disease

Pilot Randomized Control Trial of Necrotizing Enterocolitis Screening using Abdominal Radiograph versus Bowel Ultrasound plus Abdominal Radiograph in Congenital Heart Disease Patients

Multicenter, Open-Label, Dose Escalation Study to Evaluate Safety, Tolerability, and Pharmacokinetics of RLX030 in Addition to Standard of Care in Pediatric Patients from Birth to <18 years of Age, Hospitalized with Acute Heart Failure

A Phase 3b, Multicenter, Open-label, Randomized Withdrawal Trial of Effects of Titrated oral SAMSCA (tolvaptan) on Serum Sodium, Pharmacokinetics, and Safety in Children and Adolescent Subjects Hospitalized with Euvolemic or Hypervolemic Hyponatremia

QI: Severe Pediatric Burn Management Guideline Implementation

 

Yong Han

Randomized, Double-blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of SAGE-547 Injection in the Treatment of Subjects with Super-Refractory Status Epilepticus

Ventilator-Associated Infections Point Pravalence Study (VAIN)

The Relative Impact of High-Risk Unscheduled Transfers to the Pediatric Intensive Care Unit and Subsequent Mortality

Feasibility of Utilizing Near Infrared Spectroscopy (NIRS) and Comparison with Capillary Refill Time as Noninvasive Surrogate Endpoints for Goal-Directed Shock Resuscitation in Children

Pediatric Acute Respiratory Distress Syndrome Incidence and Epidemiology (PARDI)

Comparison of PEWS to other Scoring Systems in their Ability to Triage Hospital Admission Placement during Interfacility Transport

QI: Quality Improvement Analysis of the Global Pediatric Sepsis Initiative Registry

 

Steve Klem

Effect of Inhaled Nitric Oxide on Outcomes in Children with Acute Respiratory Failure using a Linked Database

 

Jenna Miller

Usage Patterns and Attitudes for Pre-hospital Providers Undergoing Multimedia-Based Education

QI: Severe Pediatric Burn Management Guideline Implementation

 

Laura Miller-Smith

 Outcomes and Complication of Pediatric Patients following Tracheotomy

A Feeding Protocol for Infants with Single Ventricle Anatomy May Decrease Morbidity and Mortality Associated with Feeding Complications

Pilot Randomized Control Trial of Necrotizing Enterocolitis Screening using Abdominal Radiograph versus Bowel Ultrasound plus Abdominal Radiograph in Congenital Heart Disease Patients

Parental Perspectives in the Pediatric Intensive Care Unit Regarding Limitations of Life-Sustaining Therapy, End-Of-Life Care, and Do-Not-Resuscitate Orders

The Impact of the Diagnosis of Non-Accidental Trauma on Family Consent for Organ Donation

Assessment of Worldwide Acute Kidney Injury (AKI), Renal Angina and Epidemiology (AWARE)

QI: Pediatric Severe TBI Guideline Implementation

QI:Standardization of Tracheostomy Education for Families

 

Erica Molitor-Kirsch

 

DVT in Children after Congenital Heart Surgery

BNP levels and Post-Extubation failure-  B-type Natriuretic Peptide:  A Potential Biomarker for Extubation Failure in Infants after Cardiac Surgery

ECMO Associated Blood Stream Infections in Children

Outcomes after Prolonged Extracorporeal Membrane Oxygenation Support in Children with Cardiac Disease- ELSO study

QI: Quality Implications of a Junctional Ectopic Tachycardia (JET) Management Protocol

QI: Impact of Standardized Anticoagulation and Bleeding Algorithms in Decreasing Bleeding Complications in Children on ECMO

 

Brian Olsen

QI: CMH Pediatric Critical Care Transport Quality Improvement Program

QI: Ground and Air Medical Quality Transport (GAMUT) Database

QI: AAP-Increasing Use of Waveform Capnography in Pediatric Patients with Advanced Airways During Interfacility Transport

 

Laura Ortmann

ICU Outcomes of Children Requiring Tracheostomy after Surgery for Congenital Heart Disease: Analysis of the Virtual PICU Performance System (VPS) Database

Incidence of Arrhythmias in Children Receiving Dexmedetomidine after Surgery for Congenital Heart Disease

NIRS Technology Development in the Pediatric Catheterization Laboratory

Long-Term Outcomes of Children Requiring Tracheostomy after Surgery for Congenital Heart Disease

Early Mobilization of Infants Intubated for Acute Respiratory Failure

QI: Quality Implications of a Junctional Ectopic Tachycardia (JET) Management Protocol

 

Jay Rilinger

Trans-Cranial Doppler Use in Identification of Neurologic Injury in Pediatric Extra-Corporeal Membrane Oxygenation Therapy

 

Paul Sheeran

Midazolam versus Dexmeditomidine Premedication in Children with Obstructive Sleep Apnea Undergoing Tonsillectomy and Adeonoidectomy

John Sommerauer

Pediatric Acute Respiratory Distress Syndrome Incidence and Epidemiology (PARDI)

 

Kelly Tieves

Assessing the Association between EPAS, Competencies and Milestones in the Pediatric Subspecialites

Pediatric Acute Respiratory Distress Syndrome Incidence and Epidemiology (PARDI)

QI: Pediatric Severe TBI Guideline Implementation

                             

Marita Thompson

QI: Severe Pediatric Burn Management Guideline Implementation

 


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