Pediatric Critical Care Medicine Research
Pediatric Critical Care Medicine Research

The Section of Critical Care at Children's Mercy Kansas City participates in PALISI (the Pediatric Acute Lung Injury and Sepsis Investigators), a multi-center research consortium.

Each of our trainees is expected to complete a minimum of one scholarly project during the course of their fellowship, resulting in the submission of a manuscript to a peer-reviewed publication. In addition, our fellows are expected to present findings at a national meeting.

A crucial first step in this process is the formation of a mentoring relationship with a faculty member (either inside or outside of our division), followed by development of a research question and specific aims and formation of a Scholarship Oversight Committee (SOC). The SOC will meet regularly with the fellow throughout his or her training to monitor the progress of the project, provide guidance and assure that the fellow is engaging in a meaningful and educational scholarly endeavor that will meet the requirements for board certification.

A few of the many research opportunities available at Children's Mercy Hospital include:

  • Personalized Medicine-Pediatric Genomic Medicine
  • Clinical Pharmacology
  • Cardiovascular Research

Critical Care Current Research Activities


Fellow Research Projects

Fellow

Project Title

Asdis Wagner

 

  • Parental Perspectives in the PICU Regarding Limitations of Life-Sustaining Therapy, End-of-Life Care, and Do-Not-Resuscitate Orders 

 

Arjun Chandran

  • Fluid Goals in Cardiac Surgery Patients in the First Post Operative Day 
Alyssa Stoner
  • Pediatric Resident Experience in Multidisciplinary in situ Mock Code Environment

 

Faculty Research Projects

Faculty 

Project Title

Andrew Ausmus
  1. A Needs Assessment of Brain Death Education in Pediatric Critical Care Medicine Fellowships

Jeremy Affolter

  1. Pediatric Cardiac Critical Care Consortium (PC4)
  2. National Pediatric Cardiology Quality Improvement Collaborative (NPC-QIC)
  3. Pediatric Acute Respiratory Distress Syndrome Incidence and Epidemiology (PARDIE) 

Geoffrey Allen

  1. Genomic Analysis of the Pediatric Systemic Inflammatory Response Syndrome
  2. The SAFE Extrapolation to Paediatric Intensive Care (SAFE-EPIC) Study
  3. Sedation Management in Pediatric Patients with Acute Respiratory Failure

Paul Bauer

  1. The Relative Impact of High-Risk Unscheduled Transfers to the Pediatric Intensive Care Unit and Subsequent Mortality
Jennifer Flint
  1. Single Ventricle Feeding Protocol- A Feeding Protocol for Infants with Single Ventricle Anatomy may Decrease Morbidity and Mortality associated with Feeding Complications including Necrotizing Enterocolitis
  2. Laparoscopic Gastrostomy Tube Placement in Patients with Complex Congenital Heart Disease
  3. Pilot Randomized Control Trial of Necrotizing Enterocolitis Screening using Abdominal Radiograph versus Bowel Ultrasound plus Abdominal Radiograph in Congenital Heart Disease Patients
  4. Multicenter, Open-Label, Dose Escalation Study to Evaluate Safety, Tolerability, and Pharmacokinetics of RLX030 in Addition to Standard of Care in Pediatric Patients from Birth to <18 years of Age, Hospitalized with Acute Heart Failure
  5. A Phase 3b, Multicenter, Open-label, Randomized Withdrawal Trial of Effects of Titrated oral SAMSCA (tolvaptan) on Serum Sodium, Pharmacokinetics, and Safety in Children and Adolescent Subjects Hospitalized with Euvolemic or Hypervolemic Hyponatremia

Yong (Kato) Han

  1. Randomized, Double-blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of SAGE-547 Injection in the Treatment of Subjects with Super-Refractory Status Epilepticus
  2. Ventilator-Associated Infections Point Pravalence Study (VAIN)
  3. The Relative Impact of High-Risk Unscheduled Transfers to the Pediatric Intensive Care Unit and Subsequent Mortality
  4. Feasibility of Utilizing Near Infrared Spectroscopy (NIRS) and Comparison with Capillary Refill Time as Noninvasive Surrogate Endpoints for Goal-Directed Shock Resuscitation in Children
  5. Pediatric Acute Respiratory Distress Syndrome Incidence and Epidemiology (PARDI)
  6. Comparison of PEWS to other Scoring Systems in their Ability to Triage Hospital Admission Placement during Interfacility Transport

Jenna Miller

  1. Usage Patterns and Attitudes for Pre-hospital Providers Undergoing Multimedia-Based Education
  2. Implementing Just In Time Clinical Resuscitation Training in the Intensive Care Unit

Laura Miller-Smith

  1. Outcomes and Complication of Pediatric Patients following Tracheotomy
  2. A Feeding Protocol for Infants with Single Ventricle Anatomy May Decrease Morbidity and Mortality Associated with Feeding Complications
  3. Pilot Randomized Control Trial of Necrotizing Enterocolitis Screening using Abdominal Radiograph versus Bowel Ultrasound plus Abdominal Radiograph in Congenital Heart Disease Patients
  4. Parental Perspectives in the Pediatric Intensive Care Unit Regarding Limitations of Life-Sustaining Therapy, End-Of-Life Care, and Do-Not-Resuscitate Orders
  5. The Impact of the Diagnosis of Non-Accidental Trauma on Family Consent for Organ Donation
  6. Implementing Just In Time Clinical Resuscitation Training in the Intensive Care Unit 

Erica Molitor-Kirsch

 

  1. DVT in Children after Congenital Heart Surgery
  2. BNP levels and Post-Extubation failure-  B-type Natriuretic Peptide:  A Potential Biomarker for Extubation Failure in Infants after Cardiac Surgery
  3. ECMO Associated Blood Stream Infections in Children
  4. Outcomes after Prolonged Extracorporeal Membrane Oxygenation Support in Children with Cardiac Disease- ELSO study

Jay Rilinger

  1. Trans-Cranial Doppler Use in Identification of Neurologic Injury in Pediatric Extra-Corporeal Membrane Oxygenation Therapy
  2. Implementing Just In Time Clinical Resuscitation Training in the Intensive Care Unit
  3. CHA Sepsis Collaborative

Paul Sheeran

  1. Midazolam versus Dexmeditomidine Premedication in Children with Obstructive Sleep Apnea Undergoing Tonsillectomy and Adeonoidectomy 

John Sommerauer

  1. Pediatric Acute Respiratory Distress Syndrome Incidence and Epidemiology (PARDI) 

Kelly Tieves

  1. Assessing the Association between EPAS, Competencies and Milestones in the Pediatric Subspecialties
  2. Pediatric Acute Respiratory Distress Syndrome Incidence and Epidemiology (PARDI)
  3. Implementation Trial of a Validated Clinical Decision Rule for Pediatric Abusive Head Trauma. CDR Implementation Trial.

Marita Thompson

  1. Neurosedative Requirements Pre and Post Extubation for ARDS Patients on ECMO
  2. Use of Delirium Score in Pediatric Critical Care
  3. Development of a bronchoscopy score for ARDS patients on ECMO
  4. CHA Sepsis Collaborative
  5. Blood Product Usage Pre and Post Development of a Piggyback Circuit Change Protocol
Asdis Wagner
  1. Parental Perspectives in the PICU Regarding Limitations of Life-Sustaining Therapy, End-of-Life Care, and Do-Not-Resuscitate Orders


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