Rheumatology Research
Rheumatology Research

The Division of Pediatric Rheumatology is dedicated to research of rheumatic diseases in children. We support investigator-initiated studies as well as pharmaceutical sponsored studies to provide cutting-edge science to our patients and families. In addition to research initiated at Children's Mercy, we are also actively involved in national and international collaborative studies. 

Current Research Areas

  • A signature for Response to Methotrexate in Juvenile Idiopathic Arthritis: We are looking for a testable folate pattern in patients on Methotrexate to find out if we can predict who will respond to Methotrexate and who will not.
  • Childhood Arthritis & Rheumatology Research registry: a national registry to collect information on children with rheumatic diseases.
  • ARCHIVE vasculitis registry: an international registry compiling clinical information in children affected with rare forms of vasculitis.
  • Development of Clinical Disease Outcome Measures for Localized Scleroderma: To collect information about your childs disease to develop a tool for your provider to decide if treatment is working well.
  • Gene Expression in Pediatric Arthritis: Develop biomarkers to accurately identify patients in who advanced therapy with either Methotrexate or anti-TNF biologics will be highly successful, and in whom anti-TNF agents can be effectively stopped.
  • BMS study: Test the efficacy of orencia administered subcutaneously in patients with juvenile idiopathic arthritis, as of right now we can only administer orencia intravenously.
  • WebSMART: A study to find out if a web-based self-management program for adolescents with arthritis can help improve disease symptoms and quality of life.


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