Children's Mercy Hospitals and Clinics is committed to advancing pediatric cancer research. Our research team participates in more than 80 clinical and laboratory cancer trials through the Children's Oncology Group and other national consortia.
Current Research Areas
Our team is currently conducting research on a broad range of topics including neuroblastoma, stem cell function in treating sickle cell disease and Chrohn's disease, new treatment for fanconi anemia and T-cell acute lymphoblasatic leukemia. Other current research projects include:
The Center for Pediatric Genomic Medicine and the Experimental Therapeutics in Cancer program are conducting breakthrough research to better understand the genetic causes of pediatric cancer.
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Bridging the Gap
The goals of this project are to assess health care provider’s knowledge of the unique needs of childhood cancer survivors, develop a face-to-face meeting and web-based educational series to improve that knowledge, and evaluate performance improvement strategies among selected clinical sites.
Parent Satisfaction in Outpatient Bone Marrow Transplantation Clinic
This two-part study will help us better understand parents' needs and concerns during the outpatient bone marrow transplantation experience.
Effects of Intrathecal Methotrexate
We're currently studying the effects of intrathecal methotrexate on folate metabolism in the cerebrospinal fluid of children with acute lymphoblastic leukemia.
Elongation Factor Protein
This study will broaden our understanding of how proteins and genes interact inside leukemia cells. We think that this will help us better understand how leukemia develops.
Pediatric Formulation of Chemotherapy
This study will help us create a child-friendly version of chemotherapy drugs that are as effective as the originally available commercial version.
Immunotherapy for GD2 Positive Tumors
Our researchers are looking to discover how joining the anti-GD2 antibody to T-cells can provide protection from viruses and kill cancer cells.